Always use common sense when using your Isis One, and be aware that some parts are very hot and move quickly. Also be careful of the sharp edges on the acrylic parts, the polycarbonate bed corners, etc.
To avoid burns, stay away from the nozzle and bed when hot, and allow ample time (5-10 minutes) for them to cool.
To avoid fire, keep flammable materials and liquids away from the printer during operation.
To avoid electrical shock, stay away from the power supply when the printer is powered, and always turn off and unplug the printer before opening the electronics box.
Do not allow unattended children or pets around your printer.